MITACHONDRAL INJECTION 100ML supplies the amino acid L-CARNITINE in the same manner as L-CARNITINE injection and paste, but has the added amino acids Phenylalanine and Isoleucine. Phenylalanine is an essential amino acid which inhibits the breakdown of opiate-like substances in the brain called encephalins. Reduced breakdown of encephalins results in increased levels of endorphins in the brain.MITACHONDRAL INJECTION 100M_x000D_n_x000D_nagainst indication_x000D_nThe use of corticosteroid preparations in acute infectious conditions should be avoided._x000D_n_x000D_nWhen used in non-acute infectious conditions, treatment should be associated with bactericidal antibiotics rather than bacteriostatics._x000D_nIn general, corticosteroids are contraindicated in viral infections and in late pregnancy, when they can induce labor._x000D_n_x000D_nThey should also not be administered to animals that are suffering from renal, cardiac and hepatic insufficiency, gastric ulcer and that present hypersensitivity to the components of the formula. Its use is not recommended in animals with diabetes mellitus, osteoporosis and those with hematocytological alterations (aplastic anemia, leukopenia, agranulocytosis, thrombocytopenia). Do not apply to newborn animals._x000D_n_x000D_ndrug interaction_x000D_nThere are risks of drug interactions occurring when phenylbutazone is administered with other non-steroidal anti-inflammatory agents, as they have a similar mechanism of action (inhibition of cyclooxygenase) and may cause an increase in the occurrence of adverse effects._x000D_nStore in a dry and cool place, protected from light, out of reach of children._x000D_n_x000D_nGrace periodhttp://www.tacomavetmedication.com
-Carnitine is also believed to have other important roles, such as preventing the toxic accumulation of acetyl CoA compounds. These compounds are trapped as carnitine esters and transported from the muscle to the liver for processing, and to the kidney for excretion. This function is not unlike a physiological buffer and so carnitine may play a protective role in preventing metabolic acidosis.
l-Carnitine is available to animals through their diet or by endogenous (within the body) biosynthesis from dietary precursors. However, as herbage and cereals have relatively low levels of carnitine, endogenous production is important.
Deficiency of l-carnitine can therefore arise when the diet is lacking in carnitine, or precursors (lysine, methionine, vitamin C, vitamin B6, niacin and iron). Signs of l-carnitine deficiency in the body are associated with a failure to utilise fatty acids for energy production and include skeletal muscle dysfunction and weakness, heart enlargement, heart failure and rhythm disturbances, and hepatic dysfunction.
d-Phenylalanine and l-isoleucine supplement the body’s requirements in situations where pain causes increased endorphin demand.
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