Dexaphenylbutazone is another active ingredient in this product belongs to NSAIDs group of drugs and its mechanism of action is different from dexamethasone. Like other NSAID drugs phenylbutazone inhibits the prostaglandin’s inflammatory effects that reduce pain and inflammation in the body and increase speed and performance during race By this mechanism other effects of prostaglandins like fever is also blocked. Besides phenylbutazone interfere in early stage of inflammation and reduce the permeability of vascular beds and prevent from edema and diapedesis (the passage of blood cells through the intact walls of the capillaries, typically accompanying inflammation)_x000D_n_x000D_ndexaphenylbutazone is a member of glucocorticoid family and like other drugs in this group it has a pharmacologic effect in all cells on the body. From different effects immunosuppressive (partially or completely suppressing the immune response of an individual) and anti inflammatory actions have been more evaluated and is indicated in these medical conditions. Glucocorticoid drugs inhibit the effects of lytic enzymes (relating to or causing lysis in tissues and cells as a destruction effect), which  are Dexaphenylbutazone released in inflammations and severe stress conditions. Also the phagocytosis effect by macrophages will be the combination of two active ingredients with different mechanism of action anti-inflammatory and pain relief of this product is predominant._x000D_n_x000D_n_x000D_nIndications of use_x000D_n_x000D_n_x000D_nAnti inflammatory, antipyretic and analgesic. Musculoskeletal inflammations like arthritis, osteoarthritis, laminitis and tendonitis in horses._x000D_n_x000D_n_x000D_nDosage and route of administration for dexaphenylbutazone_x000D_n_x000D_n_x000D_nHorses: 20 ml/day by slow IV injection that can be repeated  depending on the severity of the conditions._x000D_n_x000D_nFoals: Slow IV or deep IM: 6 – 10 ml to be repeated 24 -48 hours later depending on the severity of the case._x000D_n_x000D_n_x000D_nContraindications for dexaphenylbutazone_x000D_n_x000D_n_x000D_nIn case of vascular brittle and congestion the recommended dose must be decreased and the second dose must not be applied._x000D_n_x000D_nAlso in the animals with heart, liver or kidney problems or in the end term of pregnancy this product is contraindicated._x000D_n_x000D_n_x000D_nWithdrawal Time  for dexaphenylbutazone_x000D_n_x000D_n_x000D_nNone_x000D_n_x000D_n_x000D_nPrecautions_x000D_n_x000D_n_x000D_nAfter the use of first dose the remaining medicine can be used in 28 days._x000D_n_x000D_nProtect the vials in boxes and out of the direct sun light._x000D_n_x000D_nDo not use concomitantly with NSAIDs and other corticosteroid drugs. IV injection must be done slowly._x000D_n_x000D_nDo not use more than recommended dosage._x000D_n_x000D_nDo not sale without veterinary prescription._x000D_n_x000D_nKeep out of reach of children._x000D_n_x000D_n_x000D_nStorage conditions_x000D_n_x000D_n_x000D_nProtect in 15 – 25° C and direct sun light


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