CORTAMETHASONE

CORTAMETHASONE  It´s a Vetoquinol Dexa, 1mg / ml, excellent product for racing events, acts on many systems of the animal and the result is a remarkable increase in the performance_x000D_n_x000D_nTarget species: Equine, Camel, cattle, goats, pigs, dogs and cats._x000D_n_x000D_nIndications for use, specifying the target species_x000D_n_x000D_nIn horses, cattle, goats, pigs, dogs and cats:_x000D_n– Treatment of inflammatory, allergic or shock conditions._x000D_n_x000D_nIn cattle and goats:_x000D_n– Treatment of primary ketosis (acetoneemia, pregnancy toxemia)._x000D_n– Induction of parturition._x000D_n_x000D_nIn the equine:_x000D_n– Treatment of osteoarticular inflammatory states._x000D_n_x000D_nCons-indications_x000D_nDon´t use in animals suffering from diabetes mellitus, hyperadrenocorticism, renal insufficiency and heart failure or suffering from peptic ulcers._x000D_nDon´t use in animals with infectious disease, unless appropriate anti-infectious therapy is administered at the same time._x000D_n_x000D_nSpecial warnings for each target species_x000D_n_x000D_nIn horses and Camel, dexamethasone should only be used at the beginning of the disease during laminitis._x000D_nSee section “Use in the event of pregnancy, lactation or laying”._x000D_n_x000D_nSpecial precautions for use CORTAMETHASONE_x000D_n_x000D_nI) Special precautions for use in animals_x000D_n_x000D_nAdministration of corticosteroids at the end of pregnancy may result in premature delivery or abortion in ruminants._x000D_nExcept in the indications of acetonaemia and induction of parturition, the function of corticosteroids is to improve rather than cure. Therefore, it´s advisable to diagnose and treat the underlying disease. When used to treat shock, intravenous fluids should be administered to maintain circulation; An acid-base assessment must be carried out._x000D_n_x000D_nSpecial precautions to be taken by the person administering the veterinary medicinal product to animals_x000D_n_x000D_nIn case of accidental self-injection, seek medical advice immediately and show the package leaflet._x000D_nPersons with known hypersensitivity to the active substance or to any of the excipients should avoid contact with the veterinary medicinal product._x000D_nPregnant women should not handle this veterinary drug._x000D_n_x000D_nUndesirable effects (frequency and severity)_x000D_n_x000D_nIn prolonged use, corticosteroids such as dexamethasone may cause iatrogenic hypercorticism, polyuropolydipsia (PUPD), immunosuppression, bulimia and redistribution of the body’s lipid reserves._x000D_nThe use of corticosteroids in lactating cattle and goats may lead to a temporary decline in milk production._x000D_nInduction of parturition with corticosteroids may be associated with reduced progeny viability and increased incidence of placental retention._x000D_n_x000D_nUse in pregnancy, lactation or laying CORTAMETHASONE_x000D_n_x000D_nStudies in laboratory animals have demonstrated embryotoxic effects._x000D_nThe use of corticosteroids in pregnant females is not recommended except in ruminants to induce parturition during the last third of gestation._x000D_n_x000D_nDrug Interactions and Other Forms of Interaction_x000D_n_x000D_nActs on several systems of the animal and the result is a remarkable increase in the performance_x000D_n_x000D_nBecause corticosteroids can reduce the immune response to vaccination, dexamethasone should not be given at the same time as vaccines._x000D_nConcomitant use of non-steroidal anti-inflammatory drugs may increase the risk of ulceration of the gastrointestinal tract._x000D_n_x000D_nDosage and route of administration all species CORTAMETHASONE_x000D_n_x000D_nIntravenous or intramuscular use._x000D_nEquine, Camel, cattle, goats, pigs 0.04 to 0.10 mg / kg (4 to 10 ml / 100 kg)_x000D_nDogs, cats 0.05 to 0.10 mg / kg (0.5 to 1 ml / 10 kg)_x000D_n_x000D_nDosification & Administration for Race :_x000D_nFor professional application not detected, read the article about dexa for race_x000D_n_x000D_nFor safe application not detected pre-race: 5 ml for 5 days, suspend 2 days before the race_x000D_n_x000D_nOverdose (symptoms, emergency management, antidotes), if necessary_x000D_n_x000D_nHigh doses of corticosteroids may cause somnolence and lethargy in equines._x000D_n_x000D_nWaiting time_x000D_n_x000D_nMeat and offal: 6 days._x000D_nMilk: 3 days._x000D_n_x000D_nPharmacological Properties_x000D_n_x000D_nPharmacotherapeutic group: corticosteroids for systemic use, glucocorticoid._x000D_nATC-vet code: QH02AB02._x000D_n_x000D_nPharmacodynamic Properties_x000D_n_x000D_nDexamethasone is a potent synthetic with low mineralocorticoid activity. Dexamethasone has ten to twenty times the anti-inflammatory activity of prednisolone at an equivalent molar dose. Corticosteroids may decrease the immune response. Indeed, they inhibit capillary dilation, leukocyte migration and phagocytosis. Glucocorticoids have an effect on metabolism by increasing gluconeogenesis. Dexamethasone induces parturition in ruminants if the fetus is alive._x000D_n_x000D_nPharmacokinetic properties_x000D_n_x000D_nAfter administration of the product intramuscularly, dexamethasone is absorbed rapidly, resulting in a rapid and short-acting response. T max in cattle, goats, horses, pigs, dogs and cats is reached within 30 minutes after intramuscular administration. The T½ (half-life time) varies depending on the species between 5 and 20 hours. The bioavailability after intramuscular administration is approximately 100%._x000D_n_x000D_nPharmaceutical Information_x000D_n_x000D_nList of excipients:_x000D_n_x000D_nBenzyl alcohol (E1519)_x000D_ndimethylacetamide_x000D_nPropylene glycol_x000D_nWater for injections_x000D_n_x000D_nMajor Incompatibilities: Not known._x000D_n_x000D_nThe duration of the conversation:_x000D_n_x000D_n3 years._x000D_nAfter opening: 28 days._x000D_n_x000D_nSpecial precautions for storage_x000D_n_x000D_nAny._x000D_n_x000D_nNature and composition of primary packaging_x000D_n_x000D_nGlass bottle_x000D_nSpecial precautions to be taken when disposing of unused veterinary medicinal products or waste derived from the use of such medicinal products_x000D_n_x000D_nEmpty packagings and any residues of product should be disposed of in accordance with current practices regulated by the wastehttps://camelhorsemedrace.com/